TABLE 2.
Generalized linear models predicting HCC viability on explant histology
| Coefficient | OR (95% CI) | p | |
|---|---|---|---|
| Univariate models | |||
| Biomarker | |||
| Log10AFP | 1.36 | 3.89 (1.89, 8.00) | 0.0002 |
| AFP-L3% | 0.07 | 1.07 (1.03, 1.12) | 0.0004 |
| Log10 DCP | 1.48 | 4.40 (1.81, 10.69) | 0.001 |
| Multivariable model (3 biomarkers) | |||
| Predictor | |||
| Intercept | −0.37 | 0.69 (0.37, 1.31) | 0.26 |
| Log10AFP | 0.69 | 2.00 (0.84, 4.72) | 0.12 |
| AFP-L3% | 0.04 | 1.04 (1.00, 1.09) | 0.06 |
| Log10 DCP | 1.18 | 3.26 (1.31, 8.08) | 0.01 |
| Multivariable model (3 biomarkers and imaging) | |||
| Predictor | |||
| Intercept | −0.74 | 0.48 (0.23, 0.94) | 0.04 |
| Log10AFP | 0.72 | 2.05 (0.89, 5.07) | 0.10 |
| AFP-L3% | 0.04 | 1.04 (1.00, 1.09) | 0.07 |
| Log10 DCP | 1.06 | 2.90 (1.27, 8.11) | 0.02 |
| Imaging | 1.26 | 3.53 (1.68, 7.93) | 0.001 |
Abbreviations: AFP, alpha-fetoprotein; AFP-L3%, lens culinaris-agglutinin-reactive fraction of AFP; DCP, des-gamma-carboxy prothrombin.