Table 3.
Recurrence-related findings and number of reoperations
| Covariation | Overall series (35 pts) | Single recurrence 24 pts (69%) | Multiple Recurrences 11 pts (31%) | Statistical significance (p value) |
|---|---|---|---|---|
| Time to recurrence (median) | 47 mo | 48 mo | 57 mo | p = 0.34 |
| Topography of the recurrence at the first reoperation | ||||
| • localized-peripheral | 23 (66%) | 20 (83%) | 3 (27%) | p < 0.00001 |
| • multicentric/diffuse | 12 (34%) | 4 (17%) | 8 (73%) | |
| Extent of resection at first reoperation | ||||
| • gross-total | 26 (73%) | 22 (91%) | 4 (36%) | p < 0.00001 |
| • subtotal | 9 (27%) | 2 (9%) | 7 (64%) | |
| WHO grade and Ki67 MIB1 between initial surgery and first reoperation | ||||
| WHO grade | ||||
| • stable | 31 (89%) | 21 (87.5%) | 10 (91%) | |
| • progression | 4 (17%) | 3 (12.5%) | 1 (9%) | |
| Ki67 MIB1 | ||||
| • stable | 25 (70%) | 17 (71%) | 8 (73%) | p = 0.87 |
| • progression | 10 (30%) | 7 (29%) | 3 (27%) | |