Table 3.

Negative predictors of OS

Parameter	p-value	Hazard ratio	95%CI
Age	< 0.001	1.03	1.02–1.03
CCI	< 0.001	1.2	1.12–1.27
Focal neurologic deficits	< 0.001	1.52	1.12–1.87
Biopsy	< 0.001	1.67	1.3–2.14
Palliative therapy	< 0.001	5.22	3.56–7.67
Multifocal GBM	< 0.001	1.77	1.31–2.39
Involvement of corpus callosum	< 0.001	1.72	1.34–2.21
Ventricular contact	< 0.001	1.46	1.17–1.81