FIG. 6.

Weight and combined blepharitis and periocular disease scores in mice for 30 days following corneal scarification and infection with 2 × 10⁶ PFU per eye of KOS, KOSV2, KOSV2R, or SB5. Blepharitis is shown as a line graph with weight as a superimposed bar graph. Animals were scored on days 1 to 7, 9, 16, 23, and 30 postinfection as follows: 0, no lesions; 1, minimal eyelid swelling; 2, moderate swelling and crusty ocular discharge; 3, severe swelling, moderate periocular hair loss, and skin lesions; and 4, severe swelling with eyes crusted shut, severe periocular hair loss, and skin lesions. Data represent two independent experiments with combined and averaged scores of at least 13 mice per virus per day.