Table 1.
Baseline characteristics and follow-up duration
| All patients | Patients with DLBCL treatment | Patients with no DLBCL treatment | p value | |
|---|---|---|---|---|
| (n = 2633) | (n = 2119) | (n = 514) | ||
| Baseline characteristics | ||||
| Age, median (mean|SD) at index date | 75 (72.1|13.1) | 74 (71.1|12.9) | 80 (76.5|13.2) | < 0.001 |
| < 65 years, n (%) | 639 (24.3) | 556 (26.2) | 83 (16.1) | < 0.001 |
| 65 to 74, n (%) | 627 (23.8) | 546 (25.8) | 81 (15.8) | – |
| 75 to 84, n (%) | 1015 (38.5) | 809 (38.2) | 206 (40.1) | – |
| 85+ | 352 (13.4) | 208 (9.8) | 144 (28.0) | – |
| Sex, male, n (%) | 1343 (51.0) | 1082 (51.1) | 261 (50.8) | 0.908 |
| CCI, median (mean|SD) at index date n (%) | 8 (8.3 | 4.1) | 8 (8.6 | 4.1) | 7 (7.1 | 3.7) | < 0.001 |
| Top comorbidities at index date (ICD-10-GM), n (%) | ||||
| Primary hypertension (I10) | 1332 (50.6) | 1068 (50.4) | 264 (51.36) | 0.696 |
| Diabetes mellitus type 2 (E11) | 624 (23.7) | 486 (22.9) | 138 (26.8) | 0.061 |
| Fluid/electrolyte/acid–base imbalance (E87) | 604 (22.9) | 473 (22.3) | 131 (25.4) | 0.126 |
| Chronic kidney disease (N18) | 393 (14.9) | 281 (13.3) | 112 (21.7) | < 0.001 |
| Atrial fibrillation/flutter (I48) | 374 (14.2) | 274 (12.9) | 100 (19.5) | < 0.001 |
| Follow-up | ||||
| Duration of follow-up in months, median (mean|SD) | 21.0 (33.9 | 33.8) | 26.6 (37.2 | 33.5) | 2.9 (20.3 | 31.5) | < 0.001 |
| < 6 months, n (%) | 726 (27.6) | 422 (19.9) | 304 (59.1) | < 0.001 |
| 6 to < 12 months, n (%) | 277 (10.5) | 237 (11.2) | 40 (7.8) | – |
| 12 to < 24 months, n (%) | 396 (15.0) | 361 (17.0) | 35 (6.8) | – |
| 24 to < 48 months, n %) | 445 (16.9) | 400 (18.9) | 45 (8.8) | – |
| 48+ months, n (%) | 789 (30.0) | 699 (33.0) | 90 (17.5) | – |
| Reason for loss to follow-up, n (%) | ||||
| Death | 1567 (59.5) | 1163 (54.9) | 404 (78.6) | < 0.001 |
| End of study | 1051 (40.0) | 943 (44.5) | 108 (21.0) | – |
| End of insurance | 15 (0.5) | 13 (0.6) | 2 (0.3) | – |
CCI Charlson Comorbidity Index, DLBCL diffuse large B-cell lymphoma, ICD-10-GM International Classification of Diseases 10th Revision German Modification, SD standard deviation