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. 2024 Jun 6;14:1408238. doi: 10.3389/fonc.2024.1408238

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Copyright © 2024 Menke, Aypar, Bangs, Cook, Gupta, Hasserjian, Kong, Lin, Long, Ly, Menke, Natkunam, Ruiz-Cordero, Spiteri, Ye, Zadeh and Gratzinger

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diagnosis of all large B-cell lymphoma specimens with MYC, BCL2, and/or BCL6 FISH performed. The diagnosis was retrieved retrospectively with FISH results already incorporated. Most cases were diffuse large B-cell lymphoma (DLBCL) (n=173). High-grade B-cell lymphoma with MYC and BCL2 rearrangements (HGBCL-MYC/BCL2) (n=19) and high-grade B-cell lymphoma, NOS (HGBCL) (n=9) were smaller subsets. Burkitt lymphoma (n=5), primary mediastinal large B-cell lymphoma (PMLBCL; n=3) and T-cell, histiocyte-rich large B-cell lymphoma (TCHRLBCL; n=2) were rare in this cohort.