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. 2024 Jun 19;15(6):432. doi: 10.1038/s41419-024-06816-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A Overlap of upregulated and downregulated genes in A2780 and OVCAR3 cells when CSTF3 was knocked down. B KEGG enrichment analysis for overlap of upregulated and downregulated genes. C Overlap of differentially expressed genes (DEGs) in OVCAR3 cells when NEAT1 and NEAT1_2 were silenced. D KEGG analysis of DEGs for silencing NEAT1. E KEGG analysis of DEGs for silencing NEAT1_2. F Histogram of KEGG analysis for the independent DEGs list with NEAT1 and NEAT1_2 silenced. G KEGG enrichment analysis of the individual DEGs list with NEAT1 silenced. H KEGG enrichment analysis of the individual DEGs list with NEAT1_2 silenced. I The levels of PI3K/AKT/mTOR pathway-related proteins were detected by western blot when CSTF3 was downregulated in A2780 and OVCAR3 cells. J Western blot was used to measure the levels of PI3K/AKT/mTOR pathway-related proteins with NEAT1 or NEAT1_2 siRNA transfected into A2780 and OVCAR3 cells.