Figure 3.

The Histologically Active EoE Diagnostic Panel (HAEDP) and EoE Diagnostic Panel (EDP) share a common gene list. (A) Graphical representations of the number of genes overlapping between the EDP identified by Wen et al ⁴ and the HAEDP. Seventeen genes were common to both panels and visualised as significantly downregulated in histologically active eosinophilic oesophagitis (EoE) (B), significantly upregulated in histologically active EoE (C) and upregulated but significantly not different in histologically active EoE (D). In addition, 36 genes were uniquely found in HAEDP, and 60 genes were uniquely found in EDP. Data are represented as the normalised counts mean±SEM. *P≤0.05, **p≤0.01, ***p≤0.001 using one-way analysis of variance test followed by Holm-Šídák’s multiple comparisons test (controls n=5, EoE AF(+) n=5, EoE AF(−) n=5, EoE RF(+) n=4, EoE RF(−) n=5). IGFL1, IGF-like family member 1.