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. 2000 Oct 14;321(7266):950–953. doi: 10.1136/bmj.321.7266.950

Table 2.

Benefits of thrombolysis after acute myocardial infarction by age for men in Australia on basis of deaths from days 0-35

Age (years)
<55 55-64 65-74
Absolute risk reduction9 0.011 0.018 0.027
Proportion of population with acute myocardial infarction eligible for treatment* 0.54 0.49 0.40
Event rate of acute myocardial infarction per 100 000 137 760 1523
Number needed to treat  91  56   37
Disease impact number 169 113   93
Population impact number 123 000 14 900 6100
*

Assumes 77%, 70%, and 66% of patients in each ascending age group are admitted to hospital (due to deaths occurring before reaching hospital: WHO MONICA project monitoring trends and determinants in cardiovascular disease study, unpublished) and proportions given thrombolysis in hospital are 0.7, 0.7, and 0.6 in each ascending age group (New South Wales acute cardiac care study, unpublished). 

Based on mortality data from Australian Institute of Health and Welfare10 and morbidity data from Australian Institute of Health and Welfare national morbidity database.