Table 3.
Summary of experimental data of ADCs related research.
| Main study | Number of participants | ORR | mDOR(m) | mPFS(m) | mOS(m) |
|---|---|---|---|---|---|
| InnovaTV 201 | 27 | 22% | 6.0 | / | / |
| InnovaTV 204 | 101 | 24% | 8.3 | 4.2 | 12.1 |
| InnovaTV 206 | 17 | 29.40% | 7.1 | 3.1 | 11.4 |
| InnovaTV 205(1L TV+Pembro) | 32 | 40.60% | NR | 5.5 | NR |
| InnovaTV 205(2L/3L TV+Pembro) | 34 | 38.20% | 14 | 5.6 | 15.3 |
| InnovaTV 205(1L TV+Carbo) | 33 | 54.50% | 8.6 | 6.9 | NR |
| InnovaTV 301 | 253 | 17.80% | 5.3 | 4.2 | 11.5 |
| DESTINY-PanTumor02 | 40 | 50% | 9.8 | 7 | 13.4(All people) |
| C018 | 25 | 36.40% | 5.52 | 4.37 | NR |
| EVER-132-003 | 18 | 50% | 9.2 | 8.1 | / |
| CTR20220106 | 40 | 40.54% | NR | ||
NR, not reached.
/, not available.