Table 2. Distribution of tumors according to histopathological classification, immunohistochemical evaluation, preoperative tumor volume before (day 0) and after (day 15) treatment with sodium dichloroacetate (DCA) (n=19), and response to treatment.

Case	Histopathological classification	Immunohistochemistry		Preoperatory tumor volume		Percentage of reduction (−) or increase (+) in tumor volume	Response classification
		Ki67 (%)	Score COX-2	Before DCA treatment (day 0)	After DCA treatment (day 15)
1	Solid carcinoma	>20	2	13.8	1.3	−90.5	Reduction
2	Complex adenoma	<20	0	34.2	8.2	−76.0	Reduction
3	Solid carcinoma grade I	>20	2	95.6	25.7	−73.1	Reduction
4	Fibroadenoma	<20	2	1.4	0.5	−64.2	Reduction
5	Benign mixed tumor	<20	1	52.5	28.9	−44.9	Reduction
6	Carcinoma in mixed tumor grade II	<20	0	33.2	18.8	−43.4	Reduction
7	Carcinoma in mixed tumor grade I	>20	1	1.0	0.6	−40.0	Reduction
8	Carcinoma in mixed tumor	<20	1	13.9	9.2	−33.8	Reduction
9	Tubular carcinoma grade I	<20	1	3.9	2.7	−30.8	Reduction
10	Solid carcinoma	>20	4	16.7	11.7	−29.9	Stable
11	Complex carcinoma grade II	<20	3	85.7	68.2	−20.4	Stable
12	Carcinoma in mixed tumor grade I	<20	3	1.0	0.8	−20.0	Stable
13	in situ carcinoma	>20	4	2.1	1.7	−19.0	Stable
14	Carcinoma in mixed tumor	<20	1	3.2	2.7	−15.6	Stable
15	Solid carcinoma	<20	2	63.5	57.2	−9.9	Stable
16	Carcinoma in mixed tumor	>20	3	107.8	98.1	−9.0	Stable
17	Solid carcinoma	<20	0	124.9	121.2	−3.0	Stable
18	Solid carcinoma grade II	<20	0	8.0	7.8	−2.5	Stable
19	Carcinoma in mixed tumor	<20	0	107.7	366.0	+239.0	Progression