Figure 7.

Evaluation of ultrasound‐triggered tissue permeable hydrogels promoting microvascular remodeling in vivo. A) Permeability of fibrinogen complex solution in artificial bone and in liquid after crosslinking. B) Schematic of animal experiments. C,D). PI3K immunofluorescence expression, H) and quantitative analysis (red: PI3K gene fluorescence staining) Scale bar: 100 µm and Scale bar: 10 µm. E) Immunofluorescence expression of Akt, and I) quantitative analysis (green: Akt gene fluorescence staining). Scale bar: 100 µm. F,G) HIF‐1α immunofluorescence expression, Scale bar: 100 µm and Scale bar: 10 µm, J) and quantitative analysis (red: HIF‐1α gene fluorescence staining). Data are reported as mean ± SD, ^* p < 0.05, ^** p < 0.01.