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. Author manuscript; available in PMC: 2025 Jul 1.
Published in final edited form as: Comput Biol Med. 2024 May 23;177:108643. doi: 10.1016/j.compbiomed.2024.108643

Table 2.

Test set performance (AUC with 95% confidence intervals (CI)) of M1, M2 and CovSafeNet on D1test, D2, D3 and D4 datasets. The performance of CovSafeNet was compared with models M1 and M2 using DeLong’s test.

Model AUC (95% CI) D1test N=419 D2 N=113 D3 N=2000 D4 N=282 Combined N=2814
M1 0.850 (0.814, 0.888) 0.714 (0.612, 0.816) 0.709 (0.681, 0.738) 0.610 (0.542, 0.678) 0.655 (0.633, 0.678)
M2 0.867 (0.833, 0.901) 0.770 (0.667, 0.873) 0.697 (0.666, 0.728) 0.650 (0.579, 0.723) 0.680 (0.658, 0.702)
CovSafeNet 0.890* (0.860, 0.921) 0.769 (0.667, 0.870) 0.732 (0.704, 0.761) 0.654 (0.583, 0.724) 0.693* (0.671, 0.716)
DeLong’s Test with M1 p=0.0342 p= 0.9877 p<0.0001 p=0.812 p=0.0123
DeLong’s Test with M2 p=0.0001 p=0.0589 p=0.0548 p=0.0558 p<0.0001
*

indicates statistically significant improvement as indicated by DeLong’s test.