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| ||||||
|---|---|---|---|---|---|---|
| Compound | E/Z | Ar | IC50 (μM) | |||
| KB-3-1 | NCI-H460 | HEK-293 | MCF-7 | |||
| 203a | Z |
|
0.01 | 0.01 | 0.01 | 0.09 |
| 206a | Z |
|
0.03 | 0.01 | 0.023 | >10 |
| 206b | Z |
|
0.03 | 0.03 | 0.03 | 0.24 |
| 206c | E |
|
>10 | >10 | 2.90 | >10 |
| 206d | E |
|
>100 | >100 | >100 | >100 |
| 206e | E |
|
2.40 | >10 | 2.40 | >10 |
| 206f | Z |
|
3.10 | >10 | 3.90 | 7.70 |
| 206g | Z |
|
>100 | >100 | >100 | >100 |
| 206h | E |
|
>100 | >100 | >100 | >100 |
| Colchicine | — | — | 0.02 | 0.06 | 0.02 | 0.06 |
