Fig. 5.

Correlation between neuropsychological test (ACE-III and MMSE) and PsEV-derived AD pathology markers. Amyloid-β (1–42) β, p-Tau, IL-1β, TNF-α, GFAP, and synaptophysin protein concentration. A–F Correlation between ACE-III scores and amyloid-β (1–42) (A), pTau (B), IL-1β (C), TNF-α (D), GFAP (E), and synaptophysin (F) protein concentration. G–L A correlation between MMSE Score and amyloid-β (1–42) (G), p-Tau (H), IL-1β (I), TNF-α (J), GFAP (K), and synaptophysin (L) protein concentration. Abbreviations: ACE-III, Addenbrooke Cognitive Examination; MMSE, Mini-Mental State Examination; p-Tau, Phospho-Tau; TNF-α, tumor necrosis factor-alpha; GFAP, glial fibrillary acidic protein. Spearman correlation was used for correlation analysis