FIG. 9.

Replication of subtype B virus LAI with the core LTR of subtype E. The molecular clone pLAI and two derivatives with the LTR fragment (position −147 to −1) of subtype E (LAI-E and LAI-E^mut) were used to generate viral stocks in SupT1 cells. Infections were started with equal amounts of virus (5 ng of CA-p24). Virus replication was followed by measuring CA-p24 production in the culture supernatant. B-LAI (○) is the wild-type LAI virus; LAI-E (■) and LAI-E^mut (▴) are described in the text. Similar results were obtained in three independent infections.