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Structure of the human major histocompatibility complex (MHC) on chromosome 6, which has been fully sequenced.14 Within 3.6 megabases there are an estimated 128 expressed genes, of which 40% are predicted to have immune function. Red bars mark the locations of putative immune genes, some of which are labelled (TNF=tumour necrosis factor, LT=lymphotoxin, HSP=heat shock protein, C2 and C4=complement genes, TAP=antigen peptide transporter)
