FIG. 5.

Alignment of a portion of the E2 H domain of 15 mucosotropic human and animal papillomaviruses spanning a cluster of basic amino acids residues. Pcpv, pigmy chimp papillomavirus; Rpv, rhesus monkey papillomavirus. Dashes represent gaps introduced for maximal alignment. The cluster of basic amino acids is marked by dots. The inner bracket denotes the pentapeptide mutated to alanine in the HPV-11 E2 fusion proteins. Note that the region is flanked by helix-breaking glycine and proline residues in many of the viruses (outer bracket).