Figure 6.

Plasma expression/protein quantitative trait loci (pQTLs) in patients with ST-segment–elevated myocardial infarction (STEMI) vs controls show both condition-dependent and condition-independent changes. Plasma pQTLs in 38 patients with STEMI and 1142 general population controls.⁷ In A, a pQTL is highlighted that is universal (i.e. found in both STEMI patients and the general population), whereas in B a pQTL is highlighted that is disease-specific (i.e. only in STEMI patients) or in C disease and condition-specific (i.e. only in STEMI patients 24h after hospital admission). The number of samples for each genotype group: Table S11. *FDR-corrected significant P values; r, Spearman correlation. IL indicates interleukin; LDLR, low-density lipoprotein receptor; and MMP9, matrix metalloproteinase 9.