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. 2024 Jun 10;17(3):e004369. doi: 10.1161/CIRCGEN.123.004369

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© 2024 The Authors.

Circulation: Genomic and Precision Medicine is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 8. — Limited agreement among studies into metabolomic and lipidomic changes in tissue of patients with hypertrophic cardiomyopathy (HCM) compared with nonfailing (NF) donor tissue. A, Pie chart visualizing agreement in metabolite findings in HCM vs NF donor cardiac tissue samples; 114 metabolites were detected in at least 2 studies. Of these metabolites, 92 displayed inconsistent outcomes in HCM vs NF donor tissue. B, Table displaying consistency in lipidomic findings in HCM vs NF donor tissue. Blue and orange indicate consistently lowered and elevated levels, respectively, in HCM vs NF donors. *Derived from both metabolomics and lipidomics.