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. 2024 Jan 23;1(1):ugae001. doi: 10.1093/narmme/ugae001

Figure 4.

Figure 4.

ARM-1 reduces mutagenesis. (A) Mutation rates of S. enterica strains measured using ciprofloxacin; n = 64 (WT − ARM-1), 64 (WT + ARM-1), 52 (Δmfd − ARM-1) and 52 (Δmfd − ARM-1). Cells were grown in the presence of 100 μM ARM-1 when indicated. Error bars represent 95% confidence intervals. (B) Mutation frequency after infection of human cells measured using 5-fluorouracil; n = 30 (WT − ARM-1), 24 (WT + ARM-1), 18 (Δmfd − ARM-1) and 18 (Δmfd − ARM-1). Cells were grown in the presence of 5 μM ARM-1 when indicated. Error bars represent the SEM. Statistical significance was determined via ordinary one-way ANOVA, *P < 0.05.