Table 1.
Liver serology workup
| Variable | Reference range, adults | Result |
| Hepatitis A IgM antibody | Negative | Negative |
| Hepatitis B surface antigen | Nonreactive | Positive |
| Hepatitis B surface antibody | Nonreactive | Nonreactive |
| Hepatitis B total core antibody | Nonreactive | Positive |
| Hepatitis B IgM core antibody | Nonreactive | Positive |
| Hepatitis B DNA (IU/mL) | Undetected | 421,000,000 |
| Hepatitis C antibody | Nonreactive | Nonreactive |
| Hepatitis C RNA (IU/mL) | Undetected | Undetected |
| Hepatitis D antibody | Negative | Negative |
| Hepatitis E IgM antibody | Negative | Negative |
| Hepatitis E IgG antibody | Negative | Negative |
| Hepatitis E RNA (IU/mL) | Undetected | Undetected |
| HIV-1 antigen | Nonreactive | Nonreactive |
| HIV-1 antibody | Nonreactive | Nonreactive |
| HIV-2 antibody | Nonreactive | Nonreactive |
| CMV IgM | Negative | Negative |
| EBV viral capsid antigen IgM antibody | Negative | Negative |
| EBV DNA (copies/mL) | Not detected | Not detected |
| HSV-1 DNA (copies/mL) | Not detected | Not detected |
| HSV-2 DNA (copies/mL) | Not detected | Not detected |
| HHV-6 DNA (copies/mL) | Not detected | Not detected |
| Adenovirus DNA (copies/mL) | Not detected | Not detected |
| Anti-nuclear antibody titer | Negative | Negative |
| Anti-smooth muscle antibody | Negative | Positive (1:40 titer) |
| Anti-mitochondrial antibody | Normal: 0, borderline 0.1–0.3 | 0.1 |
| Anti-liver kidney microsomal type 1 antibody | Negative | Negative |
| IgG (mg/dL) | 610–1,616 | 706 |
| IgM (mg/dL) | 35–242 | 483 |
| IgA (mg/dL) | 85–499 | 210 |
| Ceruloplasmin (mg/dL) | 19.0–31.0 | 35.5 |
| Alpha-1 antitrypsin (mg/dL) | 100–190 | 209 |
| Ferritin (ng/mL) | 30–400 | 5,636 |
| HFE gene mutation analysis | — | Negative for C282Y and H63D |
| Thyroid-stimulating hormone (TSH) (mcunit/mL) | 0.27–4.2 | 2.01 |
| Antitissue transglutaminase IgA antibody (U/mL) | <4.0 | 1.8 |
| Antitissue transglutaminase IgG antibody (U/mL) | <6.0, weakly positive 6–9 | 8.4 |
CMV, cytomegalovirus; EBV, Epstein–Barr virus; HHV, human herpesvirus; HSV, herpes simplex virus; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M.