Table 3.

The MIC values of lincomycin for some pathogenic bacteria compared to the lincomycin levels found in tissues of broiler after oral administration for 7 or 14 days consecutively.

MIC of lincomycin (µg/mL)		Microbial	Drug level in tissues exceeds or is the same as MIC	References
Minimum	Maximum
1 62.5		Staphylococcus aureus	G1.1 and G1.2 (liver, kidney); G2.1 and G2.2 (liver)	[12, 13]
512, 125		Escherichia coli	(The drug in all tissues below MIC)	[12, 13]
512, 62.5		Pasteurella multocida	(The drug in all tissues below MIC)	[12, 13]
≤0.5 0.5	> 32	Mycoplasma sinoviae	G1.1; (liver, kidney); G1.2 (liver, kidney); G2.1 (liver, kidney, breast muscle); G2.2 (liver, kidney)	[17, 18]
1	11	Mycoplasma gallisepticum	G1.1 and G1.2 (liver, kidney); G2.1 and G2.2 (liver)	[34]
1	4		G1.1 and G1.2 (liver, kidney); G2.1 and G2.2 (liver)	[35]

G1.1 lincomycin per oral administration during 7 days, drug level detected 1 day of ALA; G1.2 lincomycin per oral administration during 7 days, drug level detected 1 week of ALA; G2.2 lincomycin per oral administration during 14 days, drug level detected 1 day of ALA; G2.2 lincomycin per oral administration during 14 days, drug level detected 1 week of ALA, ALA=After lincomycin administration, MIC=Minimum inhibitory concentration