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. 2000 Apr;74(8):3832–3841. doi: 10.1128/jvi.74.8.3832-3841.2000

TABLE 3.

Incidence of mortality after i.c. inoculationa

Inoculation Viral dose (PFU, 103) Time of death (days p.i.) Mortality (%)
KOS 0.25 0
0.5 4, 5, 5 37
0.75 10, 11 25
1.5 3, 3, 3, 4, 7 58
2.0 5, 5, 6, 7 50
3.0 2, 3, 3, 3, 3, 4, 4, 7 100
6.0 2, 3, 3, 3, 3, 3, 5, 6 100
VB 0
a

Animals were observed from 60 to 240 days p.i. There were 8 animals at each dose of HSV-1 KOS and 12 animals in the control VB group. These animals were different from those described in Table 2. Surviving animals after inoculations of 5 × 102 to 20 × 102 PFU of KOS were used in the G207 challenge studies (Table 4).