Table 1. Clinical features and complications.

First author	Symptoms/complications	Pur	Jn	Spl	SCH	Os	Valve	Culprit pathogen
Cecarelli1	Meningitis, SMA, SE	Y	N	N	N	N	Mitral	Staph. aureus
Deonarine2	Cirrhosis, CHF, spondylitis	Y	N	N	N	N	Quadrivalve	Strep. mutans
El Chami3	CHF, respiratory failure	Y	N	N	N	N	Aortic	Enterococcus faecalis
Yokota4	Mesenteric abscess	Y	N	N	N	N	Mitral	MSSA
Miridjanian5	Fever, myalgia, headache	Y	N	Y	Y	N	Aortic	Moraxella kingae
Mahmoud6	Cirrhosis, CHF, ICE	Y	N	N	N	N	Mitral	Pasteurella multocida
Tiliakes7	Polyarthralgia, ANCA+ve, splenomegaly	Y	N	N	N	N	Aortic	Strep. viridans
Messiaen8	CHF, Gln, ANCA+ve	Y	N	N	N	N	Aortic	Few bacterial colonies
Chukwurah9	Gln, ICE	Y	N	Y	N	N	Aortic	Lactobacillus, Acidophilus
Branch10	ICE	N	Y	N	Y	Y	Mitral	Pasteurella multocida
Nah11	ICE, meningitis, CHF, SE, RE	N	Y	Y	Y	N	Mitral	MRSA
Nichols12	ICE	N	Y	N	N	Y	Mitral	Strep. viridans
Yeung13	ICE, CHF, SMA, SE	N	N	Y	Y	N	Aortic	Serratin marcescens
Ching14	ICE	N	N	N	N	Y	Aortic	MSSA
Inoue15	CHF, spondylitis, septic arthritis	N	N	N	N	Y	Aortic	MSSA

Key: ANCA+ve = positive for anti-neutrophilic cytoplasmic antibodies; CHF = congestive heart failure; Gln = glomerulonephritis; ICE = intracranial embolism; Jn = Janeway lesions; MRSA = methicillin-resistant Staphylococcus aureus; MSSA = methicillin-sensitive Staphylococcus aureus; N = No; Os = Ostler’s nodules; Pur = purpura; RE = renal embolism; SCH = subconjunctival haemorrhages; SE = splenic embolism; SMA = skeletal muscle abscess; Spl = splinter haemorrhages; Y = Yes