Table 2.

Accuracy of various hormonal tests for IHH (male)

Hormonal parameters	Cut-off (≤)	AUC (95% CI)	P (ROC)	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
Basal LH (U/L)	0.35	0.629 (0.351-0.90)	0.341	57.1	33.3	28.57	62.5
Basal FSH (U/L)	1.15	0.743 (0.463-1.00)	0.072	57.1	93.3	80	82.35
Basal inhibin B (pg/ml)	79.2	0.857 (0.615-1.00)	0.008	85.7	93.3	85.7	93.3
Basal AMH (ng/ml)	16.84	0.457 (0.19-0.725)	0.751	42.9	66.7	37.5	71.43
Basal testosterone (ng/dl)	20.82	0.876 (0.723-1.00)	0.005	100	53.3	50	100
Post-triptorelin 4-hour LH (U/L)	4.84	1.00	<0.001	100	100	100	100
Post-triptorelin 4-hour FSH (U/L)	9.8	0.638 (0.378-0.899)	0.307	85.7	46.7	42.87	87.5
Post-triptorelin 24-hour testosterone (ng/dl)	34.52	0.876 (0.727-1.00)	0.005	85.7	73.3	60	91.67
Post-HCG day 4 testosterone (ng/dl)	99.7	0.962 (0.88-1.00)	0.001	85.7	93.3	85.7	93.33
Basal testosterone (ng/dl) + basal inhibin B (pg/ml)	20.82, 79.2	-	-	100	88.9	85.7	100

LH - Luteinising hormone, FSH - Follicle-stimulating hormone, AMH - Anti-Mullerian hormone, HCG - Human chorionic gonadotropin, AUC - Area under the curve, ROC - Receiver operating curve