Table 3.
Coefficient estimates, standard errors (SE), t-values, degrees of freedom (df), p-values of the GCA mixed regression models.
| Children | |||||
|---|---|---|---|---|---|
| Term | Coefficient estimate | SE | T-value | df | P-value |
| Intercept | − 9.79 | 1.49 | − 6.59 | 546.07 | < 0.001 |
| Linear component (slope) | 165.63 | 23.75 | 6.97 | 2390.11 | < 0.001 |
| Quadratic component | − 84.47 | 13.42 | − 6.29 | 558.13 | < 0.001 |
| Cubic component | 55.68 | 8.93 | 6.23 | 2479.99 | < 0.001 |
| Neurotype (autistic) | − 1.20 | 1.85 | − 0.65 | 546.07 | 0.52 |
| Sex (female) | − 12.60 | 2.19 | − 5.76 | 546.07 | < 0.001 |
| Linear component (slope) × neurotype (autistic) | 26.59 | 29.59 | 0.90 | 2390.13 | 0.37 |
| Quadratic component × neurotype (autistic) | − 8.71 | 16.72 | − 0.52 | 558.13 | 0.60 |
| Cubic component × neurotype (autistic) | 11.60 | 11.13 | 1.04 | 2479.99 | 0.30 |
| Linear component (slope) × sex (female) | 252.48 | 34.96 | 7.22 | 2390.14 | < 0.001 |
| Quadratic component × sex (female) | − 116.61 | 19.76 | − 5.90 | 558.13 | < 0.001 |
| Cubic component × sex (female) | 104.08 | 13.15 | 7.92 | 248 < 0.001 | < 0.001 |
| Neurotype (autistic) × sex (female) | 8.39 | 3.02 | 2.78 | 546.07 | 0.01 |
| Linear component (slope) × neurotype (autistic) × sex (female) | − 186.31 | 48.20 | − 3.87 | 2390.15 | < 0.001 |
| Quadratic component × neurotype (autistic) × sex (female) | 77.07 | 27.24 | 2.83 | 558.13 | < 0.001 |
| Cubic component × neurotype (autistic) × sex (female) | − 82.50 | 18.13 | − 4.55 | 248 < 0.001 | < 0.001 |
| Adolescents | |||||
| (Intercept) | − 11.04 | 0.69 | − 15.93 | 1122.84 | < 0.001 |
| Linear component (slope) | 182.03 | 11.09 | 16.42 | 4815.07 | < 0.001 |
| Quadratic component | − 99.05 | 6.12 | − 16.18 | 1309.13 | < 0.001 |
| Cubic component | 62.02 | 4.16 | 14.90 | 5017.94 | < 0.001 |
| Neurotype (autistic) | 0.34 | 0.90 | 0.37 | 1122.82 | 0.71 |
| Sex (female) | − 0.01 | 1.13 | − 0.01 | 1122.80 | 0.99 |
| Linear component (slope) × neurotype (autistic) | − 1.26 | 14.39 | − 0.09 | 4815.00 | 0.93 |
| Quadratic component × neurotype (autistic) | 3.91 | 7.94 | 0.49 | 1309.10 | 0.62 |
| Cubic component × neurotype (autistic) | 0.74 | 5.40 | 0.14 | 5017.96 | 0.89 |
| Linear component (slope) × sex (female) | 10.98 | 18.14 | 0.61 | 4814.95 | 0.55 |
| Quadratic component × sex (female) | − 4.05 | 10.02 | − 0.40 | 1309.08 | 0.69 |
| Cubic component × sex (female) | 7.61 | 6.81 | 1.12 | 5017.97 | 0.26 |
| Neurotype (autistic) × sex (female) | 2.38 | 1.59 | 1.49 | 1122.79 | 0.14 |
| Linear component (slope) × neurotype (autistic) × sex (female) | − 45.42 | 25.49 | − 1.78 | 4814.92 | 0.07 |
| Quadratic component × neurotype (autistic) × sex (female) | 22.45 | 14.07 | 1.60 | 1309.06 | 0.11 |
| Cubic component × neurotype (autistic) × sex (female) | − 19.80 | 9.57 | − 2.07 | 5017.98 | 0.04 |
| Adults | |||||
| (Intercept) | − 5.45 | 0.51 | − 10.78 | 1102.18 | < 0.001 |
| Linear component (slope) | 87.12 | 8.03 | 10.84 | 4887.84 | < 0.001 |
| Quadratic component | − 51.50 | 4.52 | − 11.40 | 1194.59 | < 0.001 |
| Cubic component | 28.66 | 3.01 | 9.51 | 5126.04 | < 0.001 |
| Neurotype (autistic) | − 0.81 | 0.68 | − 1.19 | 1102.19 | 0.23 |
| S ex (female) | − 0.14 | 0.93 | − 0.15 | 1102.20 | 0.88 |
| Linear component (slope) × neurotype (autistic) | 16.70 | 10.78 | 1.55 | 4887.86 | 0.12 |
| Quadratic component × neurotype (autistic) | − 5.84 | 6.06 | − 0.96 | 1194.60 | 0.34 |
| Cubic component × neurotype (autistic) | 6.41 | 4.04 | 1.58 | 5126.02 | 0.11 |
| Linear component (slope) × sex (female) | 5.14 | 14.81 | 0.35 | 4887.90 | 0.73 |
| Quadratic component × sex (female) | − 1.76 | 8.33 | − 0.21 | 1194.61 | 0.83 |
| Cubic component × sex (female) | 1.94 | 5.56 | 0.35 | 5126.01 | 0.73 |
| Neurotype (autistic) × sex (female) | − 1.16 | 1.26 | − 0.92 | 1102.20 | 0.36 |
| Linear component (slope) × neurotype (autistic) × sex (female) | 16.87 | 20.01 | 0.84 | 4887.90 | 0.40 |
| Quadratic component × neurotype (autistic) × sex (female) | − 13.46 | 11.24 | − 1.20 | 1194.61 | 0.23 |
| Cubic component × neurotype (autistic) × sex (female) | 6.40 | 7.50 | 0.85 | 5126.00 | 0.39 |