Comparison 1. Total thyroidectomy versus subtotal thyroidectomy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Rate of recurrent hyperthyroidism	2	350	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.14 [0.04, 0.46]
2 Permanent hypocalcaemia/hypoparathyroidism	3	393	Peto Odds Ratio (Peto, Fixed, 95% CI)	4.79 [1.36, 16.83]
3 Permanent recurrent laryngeal nerve palsy	3	393	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.45 [0.38, 5.59]
4 Regression of Graves' ophthalmopathy	2	287	Odds Ratio (M‐H, Fixed, 95% CI)	1.15 [0.64, 2.08]