Cochrane Library

1. [mh "Graves disease"] 2. (grave* near/7 (diseas* or thyrotoxicos* or hyperthyr*)):ti,ab,kw 3. (grave* near/7 (orbitopath* or ophthalmopath*)):ti,ab,kw 4. (basedow* near/7 (diseas* or syndrom*)):ti,ab,kw 5. {or #1‐#4} 6. [mh Thyroidectomy] 7. thyroidectom*:ti,ab,kw 8. #6 or #7 9. #5 and #8

MEDLINE (Ovid SP)

1. exp Graves Disease/ 2. (grave* adj6 (diseas* or thyrotoxicos* or hyperthyr*)).tw. 3. (grave* adj6 (orbitopath* or ophthalmopath*)).tw. 4. (basedow* adj6 (diseas* or syndrom*)).tw. 5. or/1‐4 6. exp Thyroidectomy/ 7. thyroidectom*.tw. 8. 6 or 7 9. 5 and 8 [10‐19:Lefebvre 2011RCT filter ‐ max. sensitivity version, without "drug therapy.fs."] 10. randomized controlled trial.pt. 11. controlled clinical trial.pt. 12. randomized.ab. 13. placebo.ab. 14. randomly.ab. 15. trial.ab. 16. groups.ab. 17. or/ 10‐16 18. exp animals/ not humans/ 19. 17 not 18 20. 9 and 19

PubMed (subsets not available on Ovid)

1. grave*[tw] AND (diseas*[tw] OR thyrotoxicos*[tw] OR hyperthyr*[tw] OR orbitopath*[tw] OR ophthalmopath*[tw]) 2. basedow*[tw] AND (diseas*[tw] OR syndrom*[tw]) 3. #1 OR #2 4. thyroidectom*[tw] OR surg*[tw] 5. #3 AND #4 6. random*[tw] OR trial[tw] OR groups[tw] 7. #5 AND #6 8. #7 NOT medline[sb] NOT pmcbook

EMBASE (Ovid SP)

1. exp Graves disease/ 2. (grave* adj6 (diseas* or thyrotoxicos* or hyperthyr*)).tw. 3. (grave* adj6 (orbitopath* or ophthalmopath*)).tw. 4. (basedow* adj6 (diseas* or syndrom*)).tw. 5. or/1‐ 4 6. exp subtotal thyroidectomy/ or exp thyroidectomy/ 7. thyroidectom*.tw. 8. 6 or 7 9. 5 and 8 [10:Wong 2006"treatment studies" filter ‐ SDSSGS version] 10. random*.tw. or clinical trial*.mp. or exp treatment outcome/ 11. 9 and 10 12. limit 11 to embase

ICTRP Search Portal (Standard search)

grave* AND thyroidectom* OR basedow* AND thyroidectom* OR grave* AND surg* OR basedow* AND surg*

ClinicalTrials.gov (Advanced search)

Conditions: grave OR graves OR basedow OR basedows OR "exophthalmic goiter" OR "exophthalmic goiters" OR "autoimmune hyperthyroidism" Interventions: thyroidectomy OR thyroidectomies OR surgery OR surgical OR surgeries