FIGURE 4.

Evaluation of the critical locations of extrachromosomal circular DNA (eccDNA) for papillary thyroid carcinoma (PTC) diagnosing. (A) Summary of the 71 crucial locations for classification model capable of distinguishing the PTC and nodular thyroid goitre (NOD) patients. (B) Area under the curve (AUC) value by Receiver Operating Characteristic (ROC) analysis using the 72 predictions and their corresponding true labels. (C) Boxplot of the 72 two‐nested predicted scores calculated by the 71 locations for PTC and NOD patients. p values are shown on the graph.