TABLE 1.
Demographic data of the cohorts studied.
| A | |||||||
|---|---|---|---|---|---|---|---|
| CBD (n = 34) | PSP (n = 98) | AD (n = 456) | LOAD (n = 363) | EOAD (n = 93) | Controls (n = 1070) | Sig. | |
| Gender (Female) | 21 (61.8%) | 40 (41.2%) | 290 (63.7%) | 250 (68.9%)* | 40 (43.5%) | 560 (53.6%) | p < 0.05; LO‐AD versus Controls, PSP and EOAD |
| Age at onset | 66.19 ± 8.01 | 67.11 ± 7.77 | 70.60 ± 9.62* | 74.28 ± 7.05* | 57.26 ± 4.50* | p < 0.05; all cohorts (except DCB with PSP) | |
| Age at death | 76.10 ± 7.04 | 76.01 ± 8.58 | 80.24 ± 9.28* | 83.40 ± 7.04* | 67.89 ± 6.09* | NA | p < 0.05; all cohorts (except DCB with PSP) |
| Disease duration | 10.12 ± 7.54 | 8.21 ± 3.91 | 9.67 ± 4.97 | 9.36 ± 4.96 | 10.79 ± 4.86* | p < 0.05; EOAD versus LOAD and PSP | |
Note: Data presented as mean ± SD or N (%).
Abbreviations: AD, Alzheimer's disease; CBD, corticobasal degeneration; EOAD, early onset AD; LOAD, late onset AD; NA, not available; PSP, progressive supranuclear palsy.
*
Statistically significant differences among groups (p < 0.05).