TABLE 4.

Presence and distribution pattern of polyglutamine inclusions in individuals with tauopathies and pathological expansions in the HTT gene.

	FxCx	SB	PhG	OTCx	MBN	GP	Putamen	Caudate	SN	MbTg	Dent Nuc	Cb
Case 1	3+	2+	2+	2+	1+	0.5	3+	2+	0.5	0	0	0
Case 2	1+	0.5	1	‐	2+	0.5	2+	2+	‐	‐	0	0
Case 3	0.5	0	0	1+	0.5	0	1+	1+	0	0	0	0
Case 5	2+	1+	3+	2+	2+	0	2+	2+	0	0	0	0
HD1	3+	2+	3+	3+	3+	2+	3+	3+	3+	2+	1+	0.5
HD2	3+	2+	3+	3+	3+	0.5	3+	3+	2+	2+	2+	0.5
HD3	3+	2+	3+	3+	3+	0.5	3+	2+	3+	2+	2+	0.5
HD4	3+	2+	3+	3+	2+	1+	3+	3+	2+	1+	1+	0.5
PSP1	0	0	0	0	0	0	0	0	0	0	0	0
PSP2	0	0	0	0	0	0	0	0	0	0	0	0
CBD1	0	0	0	0	0	0	0	0	0	0	0	0
CBD2	0	0	0	0	0	0	0	0	0	0	0	0
AD1	0	0	0	0	0	0	0	0	0	0	0	0
AD2	0	0	0	0	0	0	0	0	0	0	0	0

Note: Frequent (3+): Indicates a high prevalence or severity of polyglutamine inclusions in the respective brain region. Moderate (2+): Suggests a moderate prevalence or severity of polyglutamine inclusions. Mild (1+): Implies a mild presence or severity of polyglutamine inclusions. Isolated (0.5): Indicates sporadic or isolated instances of polyglutamine inclusions. None (0): Denotes the absence of polyglutamine inclusions in the respective brain region.

Abbreviations: AD, Alzheimer's disease; Cb, cerebellum; CBD, corticobasal degeneration; Dent Nuc, dentate nucleus; FxCx, frontal cortex; GP, globus pallidus; HD, Huntington's disease; MBN, Meynert's basal nucleus; MbTg, midbrain tegmentum; OTCx, occipitotemporal cortex; PhG, parahippocampal gyrus; Polyglutamine inclusions, frequent (3+), moderate (2+), mild (1+), isolated (0.5), and none (0); PSP, progressive supranuclear palsy; SB, subiculum; SN, substatia nigra.