Table 1.
Neuropeptides secreted from schizophrenia (SZ) and control (C) induced neurons (iNs) in the presence of KCl.
| Proneuropeptide | SZ | SZ only | C | C only | Shared | Total |
|---|---|---|---|---|---|---|
| CHGB | 6 | 0 | 18 | 12 | 6 | 18 |
| NPPC | 2 | 0 | 2 | 1 | 1 | 2 |
| NTS | 0 | 0 | 2 | 2 | 0 | 2 |
| SST | 0 | 0 | 1 | 1 | 0 | 1 |
| TMSB4X | 1 | 0 | 2 | 1 | 1 | 2 |
| TMSB10 | 1 | 0 | 1 | 0 | 1 | 1 |
| ADM | 0 | 0 | 1 | 1 | 0 | 1 |
The numbers of neuropeptides in SZ and C secretion media from iN cells treated with KCl (50 mM) derived from the indicated proneuropeptides are indicated. Neuropeptides were identified and quantitated by nano-LC-MS/MS tandem mass spectrometry and PEAKs bioinformatics as described in the methods. Comparison of the SZ and C groups show neuropeptides found in only the C group combined with those found in both SZ and C groups (shared).