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. 2024 Jun 20;14(1):100. doi: 10.1038/s41408-024-01080-0

Fig. 6. Genetic features of high risk DLBCL.

Fig. 6

A Forest plot showing enrichment of mutations and copy number events between the high and low risk groups. B Bar plot showing the distribution of LymphGen and HMRN classification in the high risk group. C Dot plot showing the percentage of samples which have mutations in the represented pathways. Red dots represent the percentage of samples in the high risk group while blue dots represent the percentage of cases in the low risk group. Shown pathways have at least a 1.3 fold increase or decrease between both groups. D Lasso regression model of the predictive value of the risk signatures alone (left panel) or with inclusion of mutations (right panel). Lasso metrics of the risk signature alone, with mutations, or with ARID1A are shown in the Table. E Kaplan−Meir curve showing event free survival of high risk DLBCL with the inclusion of ARID1A mutations.