Table 3.
Correlations between serum CXCL with clinical factors of pSS
| Clinical factors | Correlation coefficient, r (p-value) | |||
|---|---|---|---|---|
| CXCL9 | CXCL10 | CXCL11 | CXCR3 | |
| Focus score | − 0.246 (0.397) | − 0.065 (0.827) | 0.612 (0.020) | 0.441 (0.115) |
| Mean peak uptake | 0.261 (0.367) | − 0.160 (0.584) | − 0.242 (0.404) | − 0.356 (0.211) |
| Mean mean uptake | 0.153 (0.601) | − 0.240 (0.409) | − 0.332 (0.246) | − 0.356 (0.211) |
| Mean % washout | 0.291 (0.313) | − 0.332 (0.246) | − 0.418 (0.137) | − 0.169 (0.563) |
| Leukocyte | − 0.182 (0.210) | − 0.189 (0.193) | − 0.169 (0.246) | − 0.011 (0.939) |
| Hemoglobin | − 0.005 (0.972) | − 0.052 (0.722) | − 0.079 (0.592) | − 0.013 (0.927) |
| ESR | 0.249 (0.085) | 0.524 (< 0.001) | 0.707 (< 0.001) | − 0.006 (0.967) |
| CRP | 0.108 (0.458) | 0.089 (0.545) | 0.200 (0.169) | 0.394 (0.005) |
| Total protein | − 0.065 (0.659) | 0.375 (0.008) | 0.535 (< 0.001) | 0.102 (0.484) |
| Globulin | 0.036 (0.806) | 0.539 (< 0.001) | 0.639 (< 0.001) | 0.148 (0.311) |
| Complement 3 | − 0.203 (0.180) | − 0.162 (0.279) | − 0.045 (0.770) | − 0.100 (0.514) |
| Complement 4 | − 0.078 (0.609) | − 0.009 (0.952) | 0.121 (0.428) | − 0.046 (0.762) |
| RF | 0.085 (0.626) | 0.219 (0.207) | 0.463 (0.005) | 0.064 (0.716) |
| ESSDAI | 0.351 (0.013) | 0.305 (0.033) | 0.321 (0.025) | − 0.217 (0.134) |
| Schirmer test, mean | − 0.101 (0.587) | − 0.354 (0.050) | − 0.237 (0.200) | − 0.189 (0.308) |
| SWS flow rates | 0.018 (0.926) | − 0.173 (0.379) | − 0.318 (0.099) | − 0.127 (0.519) |
| UWS flow rates | − 0.069 (0.733) | − 0.249 (0.210) | − 0.171 (0.393) | − 0.240 (0.229) |
CXCL, C-X-C motif chemokine ligands; CXCR, C-X-C motif chemokine receptor; pSS, primary Sjogren’s syndrome; ESR, erythrocyte sedimentation rate; CRP, c-reactive protein; RF, rheumatoid factor; ESSDAI, European League Against Rheumatism Sjogren’s Syndrome disease activity index; SWS, stimulated whole saliva; UWS, unstimulated whole saliva
Bold values indicate significant p-value