Table 4.
The correlation between chemokine expression in minor salivary gland tissue and clinical factors of pSS
| Clinical factors | Correlation coefficient, r (p-value) | ||
|---|---|---|---|
| CXCL9 | CXCL10 | CXCL11 | |
| Focus score | 0.043 (0.791) | 0.010 (0.953) | 0.045 (0.780) |
| Mean peak uptake | − 0.352 (0.038) | 0.072 (0.681) | − 0.280 (0.103) |
| Mean mean uptake | − 0.285 (0.097) | 0.087 (0.621) | − 0.238 (0.169) |
| Mean % washout | − 0.294 (0.086) | 0.026 (0.881) | − 0.448 (0.007) |
| Leukocyte | − 0.355 (0.025) | 0.002 (0.992) | − 0.262 (0.102) |
| Hemoglobin | 0.153 (0.346) | 0.202 (0.212) | − 0.025 (0.880) |
| ESR | − 0.247 (0.135) | − 0.243 (0.142) | 0.087 (0.602) |
| CRP | 0.331 (0.042) | 0.073 (0.664) | − 0.234 (0.158) |
| Total protein | − 0.017 (0.919) | − 0.030 (0.857) | 0.213 (0.198) |
| Globulin | − 0.045 (0.788) | − 0.127 (0.446) | 0.254 (0.123) |
| Complement 3 | − 0.487 (0.006) | − 0.307 (0.099) | − 0.128 (0.501) |
| Complement 4 | − 0.205 (0.278) | − 0.164 (0.388) | 0.030 (0.874) |
| RF | − 0.120 (0.468) | 0.066 (0.690) | 0.009 (0.956) |
| ESSDAI | 0.172 (0.284) | − 0.093 (0.562) | 0.094 (0.561) |
| Schirmer test, mean | − 0.206 (0.428) | − 0.080 (0.760) | 0.139 (0.594) |
| SWS flow rates | − 0.046 (0.819) | 0.084 (0.678) | 0.111 (0.581) |
| UWS flow rates | − 0.156 (0.438) | 0.116 (0.566) | 0.213 (0.287) |
CXCL, C-X-C motif chemokine ligands; pSS, primary Sjogren’s syndrome; ESR, erythrocyte sedimentation rate; CRP, c-reactive protein; RF, rheumatoid factor; ESSDAI, European League Against Rheumatism Sjogren’s Syndrome disease activity index; SWS, stimulated whole saliva; UWS, unstimulated whole saliva
Bold values indicate significant p-value