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. 2024 Jun 7;11:1407138. doi: 10.3389/fcvm.2024.1407138

Table 4.

Compare drug response in two cell types.

Cell type Synephrine HRM
EC50 (μM) 95% CI
hiPSC-CM 3.314 1.751–9.806 40.74 ± 7.27%
NRCM 34.12 24.66–49.37 40.43 ± 8.78%

hiPSC-CM, human induced pluripotent stem cell derived cardiomyocyte; NRCM, neonatal rat cardiomyocyte; EC50, the half maximal effective concentration; 95% CI, 95% confidence interval; HRM, change of heart rate at maximal.