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PKM2 protein structure and post-translational modification of PKM2. (A) PKM2 protein structure. (B) The major post-translational modification sites of PKM2, including phosphorylation, acetylation, ubiquitination, SUMOylation and lactylation. C, cysteine; ISCD, intersubunit contact domain; K, lysine; S, serine; Y, tyrosine.
