Table 1.
KEGG enrichment analysis based on genes closely linked to TBX3 in OS samples.
| ID | Description | P-value | Type |
|---|---|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) | 3.47E-02 | Metastatic-up-positive |
| hsa04530 | Tight junction | 4.47E-02 | Metastatic-up-positive |
| hsa00592 | alpha-Linolenic acid metabolism | 4.94E-02 | Metastatic-up-positive |
| hsa00604 | Glycosphingolipid biosynthesis - ganglio series | 2.99E-02 | Metastatic-up-positive |
| hsa04110 | Cell cycle | 1.63E-12 | Primary-up-positive |
| hsa03030 | DNA replication | 1.05E-07 | Primary-up-positive |
| hsa04114 | Oocyte meiosis | 2.71E-04 | Primary-up-positive |
| hsa04914 | Progesterone-mediated oocyte maturation | 1.26E-03 | Primary-up-positive |
| hsa05214 | Glioma | 6.46E-03 | Metastatic-down-negative |
| hsa04914 | Progesterone-mediated oocyte maturation | 1.08E-02 | Metastatic-down-negative |
| hsa04110 | Cell cycle | 1.70E-02 | Metastatic-down-negative |
| hsa00790 | Folate biosynthesis | 4.19E-02 | Metastatic-down-negative |
| hsa04510 | Focal adhesion | 4.74E-07 | Primary-down-negative |
| hsa04512 | ECM-receptor interaction | 1.37E-06 | Primary-down-negative |
| hsa04350 | TGF-beta signaling pathway | 2.66E-06 | Primary-down-negative |
| hsa05165 | Human papillomavirus infection | 1.13E-04 | Primary-down-negative |
TBX3, T-box transcription factor 3; OS, osteosarcoma.