Table 2.
LPA and WGCNA Gene Cluster Information. Average posterior probabilities represent the average probability that genes belonged to their respective cluster. Average module memberships represent the average correlation of the expression of all genes in a cluster with that cluster’s first principal component. Similar LPA and WGCNA clusters are shown across from one another, with LPA clusters 6 and 7 corresponding to the WGCNA Blue cluster. Clusters with no significant GO “Biological Process” terms are denoted as “NA.”
| LPA Cluster | Number of Genes | Average Posterior Probability | Biological Processes | WGCN A Cluster | Numb er of Genes | Average Module Members hip | Biological Processes |
|---|---|---|---|---|---|---|---|
| Cluster 1 | 1,891 | 0.95 | NA | - | - | - | - |
| Cluster 2 | 932 | 0.95 | Meiosis and sensory organ development | - | - | - | - |
| Cluster 3 | 2,085 | 0.95 | NA | - | - | - | - |
| Cluster 4 | 1,582 | 0.96 | NA | - | - | - | - |
| Cluster 5 | 1,219 | 0.95 | Chromatin organization and leukocyte differentiation | Brown | 1,419 | 0.32 | Mitotic chromoso me segregation |
| Cluster 6 | 1,187 | 0.95 | Ribosomal-related activity and innate immune response | Blue | 2,772 | 0.40 | Ribosomal-related activity and RNA processing |
| Cluster 7 | 806 | 0.95 | RNA processing | ||||
| Cluster 8 | 768 | 0.95 | Translation and mitochondrial activity | Yellow | 646 | 0.33 | Translation and mitochondrial activity |
| Cluster 9 | 1,113 | 0.95 | Intercellular and cell membrane-related activity | - | - | - | - |
| Cluster 10 | 817 | 0.97 | Synapse activity and morphogenesis | - | - | - | - |
| Cluster 11 | 981 | 0.93 | NA | - | - | - | - |
| - | - | - | - | Black | 874 | 0.33 | NA |
| - | - | - | - | Pink | 284 | 0.14 | B-cell receptor signaling |