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MCM8 knockdown suppresses growth and migration in vivo. (A) Construction of a nude mouse xenograft model using cells transfected with shMCM8 and shCtrl. Tumours were photographed after their removal at 35 days. (B, C) Tumour growth curves and comparison of tumour weights between the shCtrl and shMCM8 groups. (D, E) Comparison of fluorescence intensity in mice in the shMCM8 and shCtrl groups. **p < 0.01, ***p < 0.001.
