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. 2024 Jun 21;28(12):e18488. doi: 10.1111/jcmm.18488

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© 2024 The Author(s). Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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MCM8 promotes lung cancer growth and migration by upregulating DNAJC10. (A) DNAJC10 expression in A549 and H1299 cells transfected with shCtrl, shMCM8, or shMCM8+DNAJC10, detected by western blot. (B) MTT assay of cell proliferation in the three groups. (C) Colony formation assay to determine cell colony numbers in the three groups. (D) Transwell assays to determine cell migration ability in the three groups. (E) DNAJC10 expression in H1975 cells transfected with Ctrl, MCM8, or MCM8+shDNAJC10, determined by western blot. (F) MTT assay of cell proliferation in the MCM8 and MCM8 + shDNAJC10 groups. (G) Colony formation assay in the MCM8 and MCM8+shDNAJC10 groups. (H) The results of transwell assays in the MCM8 and MCM8+shDNAJC10 groups. *p < 0.05, **p < 0.01, ***p < 0.001.

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