Collecting phosphorescence
lifetime readings from an in vivo biosensor.
In the excitation phase, the reader head emits red light to excite
the biosensor’s phosphors, which begin to phosphoresce. In
the emission phase, the reader head detects the infrared light emitted
from the biosensor. The length of time before the phosphorescence
is quenched is dependent on the oxygen interactions with the phosphors,
allowing oxygen levels to be quantified. Phosphorescence lifetime
measurements are unaffected by the implantation depth, which allows
the optoelectronic components to remain outside the body, creating
smaller and less invasive biosensors.