FIG 1.

CONSORT diagram. ^aOther reasons included clinical progression (n = 2), and one each of patient could not wait for centralized review, patient went for laparoscopic surgery, patient did not meet eligibility criteria, rapid progression of malignant neoplasm disease, and not possible to obtain a tumor sample. ^bOther reason was patient had myocardial infarction (n = 1). ^cOther reasons included one each of INV decision, patient request, physician decision, total gastric surgery, clinical progression, and additional reasons. ^dOther reasons included patient request (n = 2), and one each of INV decision, clinical progression, and bedridden patient. AE, adverse event; INV, investigator.