TABLE 1.
Comparison of nucleotide and amino acid sequences of PERV-B(33) and PERV-B(43) gag, pro-pol, and env ORFs with other viral genomesa
| Virus | % Nucleotide identity (% amino acid identity) with PERV-B(33) gene (protein)
|
||
|---|---|---|---|
| gag | pro-pol | env | |
| PERV-B(43) | 99.8 (99.8) | 99.9 (99.6) | 99.7 (99.2) |
| PERV-PK28/29 | 99.6 (99.0) | 99.8 (99.7) | 99.7 (99.2) |
| PERV-MSL | 94.3 (94.5) | 96.7 (96.9) | 74.0 (69.0) |
| BaEV | 62.0 (54.0) | 63.2 (63.0) | 53.0 (33.0) |
| FeLV | 58.0 (51.1) | 61.3 (61.0) | 57.0 (48.0) |
| GaLV | 66.0 (63.0) | 66.0 (68.0) | 59.0 (51.9) |
| MoMLV | 61.0 (53.0) | 64.0 (62.0) | 58.0 (49.3) |
a
One frameshift in PERV-PK28/29 is required to maintain colinearity with the pol ORFs. The start codon of PERV-B(33) env (nt 6189 to 6191) was restored to create colinear ORFs. Homology scores were revealed using sequence analysis software DNASIS (Hitachi).