Figure 2.
Promising and novel immunotherapeutic strategies. CAR, chimeric antigen receptor; CTLA-4, cytotoxic T lymphocyte antigen-4; ICOS, inducible costimulator; LAG3, lymphocyte-activation gene 3; LILRB, leukocyte immunoglobulin-like receptor family; mRNA, messenger RNA; NK cell, natural killer cell; OX40, tumor necrosis factor receptor superfamily member 4; PD-(L)1, PD-1/PD-L1 axis; SLAMF7, SLAM family member 7; TCR, T cell receptor; TIGIT, T cell immunoreceptor with Ig and ITIM domains; TIM3, T cell immunoglobulin and mucin domain-containing protein 3; TME, tumor microenvironment; 4-1BB, tumor necrosis factor receptor superfamily member 9.