TABLE 4.
HRs for kidney graft loss by donor age group
| Variable |
Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Recipient age (per year) | 1.06 | 1.05-1.06 | <0.001 | 1.04 | 1.04-1.05 | <0.001 |
| Male recipient | 1.22 | 1.03-1.44 | 0.019 | 1.16 | 0.98-1.37 | 0.079 |
| Diabetes | 1.23 | 1.05-1.45 | 0.010 | 1.19 | 1.01-1.40 | 0.035 |
| CMV seropositive recipient | 1.17 | 0.97-1.41 | 0.097 | 0.96 | 0.80-1.16 | 0.66 |
| Time on dialysis (per year) | 1.12 | 1.07-1.16 | <0.001 | 1.14 | 1.09-1.19 | <0.001 |
| Donor age group | ||||||
| 45–54 y | Reference | Reference | ||||
| 60–69 y | 2.06 | 1.68-2.52 | <0.001 | 1.63 | 1.32-2.01 | <0.001 |
| ≥70 y | 3.15 | 2.55-3.88 | <0.001 | 1.94 | 1.54-2.45 | <0.001 |
| Male donor | 0.97 | 0.83-1.14 | 0.74 | |||
| ≥1 HLA-DR mismatches | 1.09 | 0.93-1.28 | 0.29 | |||
| HLA class I and/or II PRA | 1.05 | 0.86-1.28 | 0.66 | |||
| Cold ischemia time (per hour) | 1.00 | 0.98-1.01 | 0.59 | |||
| Delayed graft function | 1.55 | 1.25-1.94 | <0.001 | 1.39 | 1.11-1.74 | 0.004 |
CI, confidence interval; CMV, cytomegalovirus; HR, hazard ratio; PRA, panel-reactive antibody.