TABLE 5.
HRs for death-censored kidney graft loss by donor age group
| Variable |
Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Recipient age (per year) | 0.99 | 0.98-1.01 | 0.28 | 0.98 | 0.96-0.99 | 0.001 |
| Male recipient | 1.19 | 0.85-1.65 | 0.31 | |||
| Diabetes | 1.46 | 1.06-2.01 | 0.021 | 1.42 | 1.03-1.95 | 0.034 |
| CMV seropositive recipient | 0.80 | 0.57-1.12 | 0.19 | |||
| Time on dialysis (per year) | 1.10 | 1.02-1.20 | 0.019 | 1.07 | 0.98-1.17 | 0.11 |
| Donor age group | ||||||
| 45–54 y | Reference | Reference | ||||
| 60–69 y | 1.56 | 1.06-2.30 | 0.024 | 1.75 | 1.18-2.60 | 0.005 |
| ≥70 y | 2.25 | 1.51-3.36 | <0.001 | 3.20 | 2.04-5.00 | <0.001 |
| Male donor | 0.95 | 0.70-1.30 | 0.77 | |||
| ≥1 HLA-DR mismatches | 1.17 | 0.84-1.62 | 0.36 | |||
| HLA class I and/or II PRA | 1.39 | 0.97-2.01 | 0.074 | 1.38 | 0.95-1.99 | 0.088 |
| Cold ischemia time (per hour) | 0.99 | 0.96-1.02 | 0.62 | |||
| Delayed graft function | 2.14 | 1.45-3.17 | <0.001 | 1.95 | 1.31-2.90 | 0.001 |
CI, confidence interval; CMV, cytomegalovirus; HR, hazard ratio; PRA, panel-reactive antibody.