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Transactivation of EFV promoters upon ORF1 expression and cross-reactivity between HFV and EFV
| Construct | Fold increasea
|
|||
|---|---|---|---|---|
| COS cells
|
ED cells
|
|||
| EFV Tas | HFV Tas | EFV Tas | HFV Tas | |
| pGL3basic | 2 | 0.5 | 2 | 4 |
| EFV LTR | 1,058 | 1 | 260 | 2 |
| EFV IP | 184 | ND | 123 | ND |
| EFV U3R | 4,015 | ND | 1,141 | ND |
| HFV LTR | 2 | 40 | 2 | 2 |
Values are from three independent transfection experiments performed in duplicate. ND, not determined.
