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. 2024 Jun 17;17:3879–3891. doi: 10.2147/JIR.S464789

Figure 4.

Figure 4

ROC curves of sTREM-1 and main clinical parameters for severity and prognosis of COVID-19 patients. (A) Predicting severity of COVID-19 patients. The area under the curve (AUC) for sTREM-1 was 0.762 (95% confidence interval [CI]: 0.669–0.855); PCT, AUC was 0.714 (95% CI: 0.607–0.822); CRP, 0.682 (95% CI: 0.577–0.787); HGB, AUC was 0.509 (95% CI: 0.395–0.623); Albumin, 0.673 (95% CI: 0.562–0.784); D-dimer, AUC was 0.654 (95% CI: 0.532–0.776); eGFR, AUC was 0.606 (95% CI: 0.496–0.717); LCR, AUC was 0.691 (95% CI: 0.585–0.796); CAR, AUC was 0.689 (95% CI: 0.584–0.793). (B) Predicting prognosis of COVID-19 patients. sTREM-1, AUC 0.805 (95% CI: 0.697–0.914); PCT, AUC 0.710 (95% CI: 0.565–0.855); CRP, AUC 0.821 (95% CI: 0.719–0.924); HGB, AUC 0.665 (95% CI: 0.515–0.814); Albumin, AUC 0.721 (95% CI: 0.575–0.867); D-dimer, AUC 0.687 (95% CI: 0.529–0.846); eGFR, AUC 0.685 (95% CI: 0.545–0.824); LCR, AUC 0.801 (95% CI: 0.691–0.912); CAR, AUC 0.829 (95% CI: 0.732–0.927).

Abbreviations: TPR, true positive rate; FPR, false positive rate; sTREM, soluble Triggering Receptors Expressed on Myeloid Cell; PCT, Procalcitonin; CRP, C-reactive protein; HGB, Hemoglobin; eGFR, estimated glomerular filtration rate; LCR, Lymphocyte-to- C-reactive protein ratio; CAR, C-reactive protein-to-albumin ratio.